Have Knowledge Of Gas Chromatography Advantage And Application

Normal applications of GC include testing the purity of a specific material, or separating the various components of a mixture the relative amounts of these components may also be ascertained. In some scenarios, GC might help in identifying a chemical. In preparative chromatography, GC can be used to prepare pure compounds from a mix. In gas Chromatography, the moving phase or mobile phase is a carrier gas, usually an inert gas such as helium or an unreactive gas like nitrogen. The stationary phase is a microscopic coating of liquid or polymer on an inert solid support, within a sheet of glass or metal tubing called a column a homage to the fractionating column used in distillation. The device used to perform gas chromatography is referred to as a gas chromatograph or aerograph, gas separator.

Gas Chromatography

The Gaseous compounds being examined interact with the walls of this column, which can be coated with different stationary phases. This causes each compound to elute in a different time, called the retention period of the chemical. The comparison of retention times is what gives GC its analytical usefulness. Gas Chromatography is in principle very similar to column chromatography in addition to other types of chromatography, such as HPLC, TLC, but has many noteworthy differences. Firstly, the practice of dividing the chemicals in a mixture is performed between a liquid stationary phase and a gas moving stage, whereas in column chromatography the stationary phase is a solid and the moving phase is a liquid. Hence the entire name of this process is Gas-liquid chromatography, referring to the mobile and stationary phases, respectively.

Second, the column by which the gas phase passes is located in an oven where the temperature of this gas can be controlled, whereas column chromatography typically doesn’t have such temperature controller. Thirdly, the concentration of a chemical in the gas phase is only a function of the vapor pressure of the gas. Best gas chromatography is also like fractional distillation, because both procedures separate the constituents of a mixture primarily based on boiling point or vapor pressure differences. But fractional distillation is typically utilized to separate components of a mixture on a large scale, whereas GC may be used on a much smaller scale i.e., microscale. Gas Chromatography is also sometimes called vapor-phase chromatography VPC, or gas-liquid partition chromatography GLPC. These alternative names, along with their Respective abbreviations, are often found in scientific literature. Strictly speaking, GLPC is the most appropriate language, and is thus preferred by many authors.